Journal: Molecular psychiatry

Article Title: Integrative omics of schizophrenia: from genetic determinants to clinical classification and risk prediction

doi: 10.1038/s41380-021-01201-2

Figure Lengend Snippet: Resources and tools for Omics studies.

Article Snippet: , Epigenomics , 3DIV , 3D-genome Interaction Viewer and database for Hi-C and pcHi-c data , http://kobic.kr/3div.

Techniques: Expressing, Sequencing, Microarray, Imaging, Ligand Binding Assay, In Situ Hybridization, DNA Methylation Assay, Mass Spectrometry, Membrane, Genome Wide, Functional Assay, Labeling

Journal:

Article Title: Characterization of Chromosome Ends in the Filamentous Fungus Neurospora crassa

doi: 10.1534/genetics.107.084392

Figure Lengend Snippet: Telomere restriction profiles of the N. crassa OR strain. Genomic DNA was digested with HindIII plus NotI and fractionated by electrophoresis through agarose gels. The gels were blotted to nylon membranes and probed with the 32P-labeled telomere repeat sequence. The resulting phosphorimages are shown. (A) HindIII/NotI restriction profile of OR. The positions of size markers are shown on the left (in kilobases) and hybridizing bands are numbered, from largest to smallest, on the right. The corresponding TelContig numbers are shown in parentheses. Asterisks mark bands whose TelContig associations were confirmed by characterizing the relevant cosmid clones. Bands 14 and 15 do not reproduce well but were clearly visible upon overexposure of the phosphorimage. (B) Telomere profiles of microconidial isolates of the OR strain. Telomere bands are numbered from largest to smallest. The fragment marked with an asterisk is the only one that did not segregate with the mapping population.

Article Snippet: Terminal gene analysis: We identified genes that were contained within 50 kb of each telomere by inspecting gene predictions from the N. crassa genome database (Assembly 7, version 3) at the Broad Institute ( http://www.broad.mit.edu/annotation/genome/neurospora ).

Techniques: Electrophoresis, Labeling, Sequencing, Clone Assay

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Caspofungin Affects Growth of Paracoccidioides brasiliensis in Both Morphological Phases ▿ †

doi: 10.1128/AAC.00617-10

Figure Lengend Snippet: Transmission (TEM) and scanning (SEM) electron micrographs of P. brasiliensis Pb73 in its mycelial phase. (A, B, and C) TEM of cultures grown for 4 days in the absence (A and B) and presence (C) of caspofungin (1 μg/ml). (D) Corresponding SEM for panels A and B. (E) Corresponding SEM of panel C. Cell wall roughness, membrane deterioration, and disappearance of hyphal septa, with concurrent cytoplasmic disorganization, were the effects of caspofungin exposure. Similar results were obtained with strain Pb300. Measuring scales are shown in the micrographs.

Article Snippet: This does not seem to apply to the β-1,3-glucan synthase in our P. brasiliensis isolates, inasmuch as their sequences on their hot spot 1 and 2 regions and those downloaded from the publicly released P. brasiliensis genomes (Pb01, Pb03, and Pb18; Broad Institute, MIT) are 100% identical.

Techniques: Transmission Assay, Membrane

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Caspofungin Affects Growth of Paracoccidioides brasiliensis in Both Morphological Phases ▿ †

doi: 10.1128/AAC.00617-10

Figure Lengend Snippet: Transmission (TEM) and scanning (SEM) electron micrographs of P. brasiliensis Pb73 in its yeastlike phase. (A and B) TEM of cells grown for 4 days in the absence (A) and presence (B) of caspofungin (1 μg/ml). (C and D) Corresponding SEM for panels A and B, respectively. An abnormal cell wall layering is observed under the effect of caspofungin, together with membrane detachment and cytoplasmic disorganization. Similar results were obtained with strain Pb300. Measuring scales are shown in the micrographs.

Article Snippet: This does not seem to apply to the β-1,3-glucan synthase in our P. brasiliensis isolates, inasmuch as their sequences on their hot spot 1 and 2 regions and those downloaded from the publicly released P. brasiliensis genomes (Pb01, Pb03, and Pb18; Broad Institute, MIT) are 100% identical.

Techniques: Transmission Assay, Membrane

Journal: Antimicrobial Agents and Chemotherapy

Article Title: Caspofungin Affects Growth of Paracoccidioides brasiliensis in Both Morphological Phases ▿ †

doi: 10.1128/AAC.00617-10

Figure Lengend Snippet: Infrared spectra of α-1,3-glucan (A), laminarin (β-1,3-glucan) (B), chitin (C), fraction 1 from P. brasiliensis Pb73 yeastlike phase (D), fraction 1 from P. brasiliensis Pb73 mycelial phase (E), fraction 2 from P. brasiliensis Pb73 yeastlike phase (F), and fraction 2 from P. brasiliensis Pb300 yeastlike phase (G).

Article Snippet: This does not seem to apply to the β-1,3-glucan synthase in our P. brasiliensis isolates, inasmuch as their sequences on their hot spot 1 and 2 regions and those downloaded from the publicly released P. brasiliensis genomes (Pb01, Pb03, and Pb18; Broad Institute, MIT) are 100% identical.

Techniques: